Daxxify was developed by the manufacturer Revance Therapeutics. Studies showed the drug can temporarily improve “moderate to severe frown lines” in adults for a median duration of six months, which is up to two months longer than the period generally provided by Botox.
Like Botox, Daxxify is an acetylcholine release inhibitor and neuromuscular blocking agent. This means blocking certain chemical signals from nerves, mostly signals that cause muscles to contract, and temporarily relaxing the facial muscles that cause wrinkles.
However, Daxxify uses peptide exchange technology, which allows it to attach to the receptor more effectively and also accounts for the longer-lasting results. Currently, Daxxify is also the only neuromodulator that is free from human serum albumin, a protein found mostly in human blood or animal-based components.
Whereas Botox can last approximately 3 – 4 months, Daxxify has shown to last up to 9 months with the median duration of 6 months – this is great news for our patients!
In addition to reducing the appearance of fine lines and wrinkles, Daxxify can also used to treat conditions such as neck spasms, excessive sweating, an overactive bladder, and lazy eye.
Daxxify was found to be “generally safe and well tolerated” with no serious treatment-related adverse events reported in during the clinical trials.